Protein Modification Reagents
Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-OH | 2055041-39-7 | MFCD29918232 | 96.9% | 706.78 g/mol | C33H50N6O11 | 50 MG
Mal-PEG4-Val-Cit-PAB-OH is a cleavable four-unit polyethylene glycol (PEG) linker used to connect an antibody and a cytotoxic payload in antibody-drug conjugate (ADC) synthesis. It contains a maleimide reactive group for thiol coupling, a PEG4 spacer, a Val-Cit protease-cleavable dipeptide, and a para-aminobenzyl (PAB) self-immolative spacer that enables intracellular release of payloads.
- Cleavable four-unit PEG linker enabling protease-mediated release.
- Maleimide functional group for thiol conjugation.
- Val-Cit dipeptide designed for cathepsin B cleavage.
- PAB self-immolative spacer to promote efficient payload release.
- Suitable for ADC synthesis and bioconjugation workflows.
Medchemexpress LLC Dbco-PEG4-acid | 2110448-99-0 | 98.9% | 10MG
Dbco-PEG4-acid | 2110448-99-0 | 98.9% | 10MG
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | MFCD13184948 | >90% | 388.37 g/mol | C15H24N4O8 | 50 MG
N3-PEG4-C2-NHS ester is an azide-functionalized, non-cleavable polyethylene glycol (PEG) linker containing an N-hydroxysuccinimide (NHS) ester for amine coupling and an azide (N3) group for click chemistry applications such as antibody-drug conjugate (ADC) synthesis and bioconjugation.
- Azide-functionalized 4-unit PEG linker suitable for bioconjugation.
- N-hydroxysuccinimide (NHS) ester for efficient amine coupling.
- Compatible with copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- High solubility in DMSO; stock solutions commonly prepared per datasheet guidance.
- Storage recommendations: pure form -20°C up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | MFCD13184948 | 98.9% | 388.37 g/mol | C15H24N4O8 | 100 MG
N3-PEG4-C2-NHS ester is an azide-terminated polyethylene glycol (PEG4) N-hydroxysuccinimide (NHS) ester used as a bifunctional linker for bioconjugation and click-chemistry applications, including antibody-drug conjugate assembly and labeling of biomolecules.
- Azide functional group enables copper-catalyzed and strain-promoted click reactions.
- NHS ester reacts readily with primary amines to form stable amide bonds.
- Peg4 spacer provides hydrophilicity and conformational flexibility.
- High purity supports reliable research-grade conjugation.
- Stability under recommended cold-storage conditions for long-term use.
Medchemexpress LLC Fmoc-NH-PEG4-CH2COOH | 437655-95-3 | 99.1% | 473.52 | C25H31NO8 | 250 MG
Fmoc-NH-PEG4-CH2COOH is an Fmoc-protected PEG4 linker with a terminal carboxylic acid. It serves as a cleavable spacer in antibody-drug conjugate and PROTAC assembly, and as a pegylated spacer for peptide conjugation to increase solubility and provide a site for functionalization.
- Fmoc-protected amine with terminal carboxylic acid
- Peg4 spacer increases solubility and flexibility
- Suitable for antibody-drug conjugate (ADC), proteolysis-targeting chimera (PROTAC), and peptide conjugation chemistries
- Available in small-scale quantities for synthesis and method development
- Store at low temperature in a sealed container to minimize moisture exposure
Medchemexpress LLC Bcn-peg3-biotin | 1263166-92-2 | 95.0% | 594.76 | C29H46N4O7S | 5 MG
BCN-PEG3-Biotin is a biotinylated, non-cleavable PEG3 linker containing a bicyclononyne (BCN) group used for copper-free click chemistry and the synthesis of antibody-drug conjugates and bioconjugation workflows.
- Non-cleavable PEG3 linker enabling spacer functionality and biotin capture.
- BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide partners.
- Purity 95.0% and molecular weight 594.76.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Powder stable at -20°C for up to 3 years; in solvent store at -80°C for long-term stability.
Med Vet International Timolol Maleate (Generic Timoptic) Solution, 0.5%, 15mL
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Timolol Maleate is a generic version of Timoptic. Ophthalmic Timolol is in a class of medications called beta-blockers. It is an ophthalmic solutions that is used to decrease pressure in the eye.
Broadpharm Fmoc-N-amido-PEG4-acid.CAS:557756-85-1.Formula: C26H33NO8
Fmoc-N-amido-PEG4-acid.CAS:557756-85-1.Formula: C26H33NO8
